- Erectile Dysfunction
Sildenafil vs. tadalafil: what’s the difference?
Written by: Editors
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Being unable to achieve or maintain an erection can have a significant impact on quality of life and overall well-being. This issue may stem from either physical or psychological causes. Occasionally, a man may experience difficulty achieving an erection without it being a cause for concern. However, if it occurs more frequently, it can lead to distress. This may result in stress, which can, in turn, exacerbate erectile dysfunction. Fortunately, treatments such as sildenafil and tadalafil are available to help. In this article, we’ll explore what these medications are and how they differ.
Sildenafil, commonly recognised as Viagra, is the active ingredient in this medication. It belongs to a group of medicines known as PDE5 inhibitors and works quickly, typically within around 30 minutes. It is primarily prescribed to treat erectile dysfunction by temporarily increasing blood flow to the penis. This makes it easier to achieve and maintain an erection during sexual stimulation. Sildenafil is often chosen for its rapid onset and proven effectiveness.
What is tadalafil?
Tadalafil is the active ingredient in Cialis. Similar to sildenafil, it is a PDE5 inhibitor with a comparable mechanism of action. However, tadalafil has a significantly longer duration of effect, which allows for greater sexual spontaneity. It also takes approximately 30 minutes to start working and can be taken daily (with a maximum of one tablet per day).
These medications do not directly cause an erection or induce sexual arousal. Instead, they facilitate the process of achieving an erection by improving blood flow, which may also enhance sexual confidence.
The differences between these medications
Both medications are designed to treat erectile dysfunction and work in similar ways. However, there are key differences, particularly in their duration of action. The table below outlines the main distinctions:
Comparison: sildenafil vs. tadalafil
Feature | Sildenafil (Viagra) | Tadalafil (Cialis) |
|---|---|---|
Active ingredient | Sildenafil | Tadalafil |
Indication | Erectile dysfunction | Erectile dysfunction |
Type of medication | PDE5 inhibitor | PDE5 inhibitor |
Onset time | ± 30–60 minutes | ± 30 minutes |
Peak effect | 1 hour | 2–4 hours |
Duration of effect | 4 to 5 hours | Up to 36 hours |
Frequency | Max. 1 tablet per day | Daily or as needed (max. 1 per day) |
Administration | Swallowed whole with water | Swallowed whole with water |
Use with food | Possible, but heavy meals may delay effect | Possible, no impact on effect |
Common side effects | Headache, flushing, vision issues, cold symptoms, muscle pain, nausea | Headache, back pain, muscle pain, flushing, cold symptoms, nausea |
Preferred by | Men seeking a shorter duration and quick onset | Men preferring more spontaneity due to longer duration |
Prescription Required | Yes | Yes |
The choice between these medications is partly personal and should take into account factors such as medical history.
It is advisable to identify and address the cause of erectile problems with a doctor.
When is use not recommended?
In certain circumstances, the use of sildenafil (Viagra) and tadalafil (Cialis) is not recommended. This is why these medications are only available via prescription. At Dokteronline, you can complete an online medical questionnaire, which will be reviewed by one of the collaborating doctors to determine if the requested medication is suitable for you.
Use is not recommended in the following cases:
- Allergy or hypersensitivity to any of the ingredients;
- Use of nitrates or medications that release nitric oxide (always consult your doctor!);
- Severe heart or liver conditions;
- Uncontrolled low or high blood pressure;
- History of vision loss due to non-arteritic anterior ischemic optic neuropathy (NAION).
Extra caution is advised in the following situations:
- Penile deformities, sickle cell anaemia, multiple myeloma, or leukaemia;
- Severe kidney problems;
- Stomach ulcers or bleeding disorders;
- Sudden decrease or loss of vision.
Conclusion
Do not let erectile dysfunction go untreated. Both sildenafil (Viagra) and tadalafil (Cialis) can be effective options for managing your symptoms. While they work in similar ways, one offers a longer duration of action than the other. The best choice for you depends on your individual circumstances. The collaborating doctors at Dokteronline can help create a tailored treatment plan. Use the online decision aid to explore what might work best for you.