Janumet is a medication that combines two active ingredients, sitagliptin, and metformin. Sitagliptin works by increasing the levels of incretin hormones in your body, helping to control blood sugar levels. Metformin works by decreasing glucose production in the liver and improving insulin sensitivity. Janumet is suitable for adults with type 2 diabetes who need help to manage their blood sugar levels effectively.
About Janumet
Dosage and usage
You should take Janumet exactly as prescribed by your healthcare provider. The typical starting dose is one tablet twice a day with meals. Your doctor may adjust the dosage based on your individual needs. The maximum recommended dose is 100 mg sitagliptin/2000 mg metformin per day. If you experience any unusual symptoms or side effects, contact your doctor promptly.
What Janumet contains
Each Janumet tablet contains 50 mg sitagliptin and 500 mg metformin (as immediate-release). The inactive ingredients include microcrystalline cellulose, povidone, sodium stearyl fumarate, and other components.
Side effects
Common side effects of Janumet may include nausea, stomach upset, diarrhoea, or headache. Serious side effects like lactic acidosis (symptoms include muscle pain or weakness, trouble breathing, dizziness) require immediate medical attention. If you have signs of an allergic reaction such as rash, itching, or swelling, seek medical help promptly.
Precautions
Do not take Janumet if you have kidney problems, metabolic acidosis, or a history of allergic reactions to any of its components. Inform your doctor about your medical history and current medications to prevent potential interactions. If you have heart issues or are on specific medications, consult your healthcare provider before using Janumet.
Sources
Cerner Multum. Inc, 1996-2019, Online, Drug Metformin and Sitagliptin, [Accessed on the 15th of August 2019], Available at: https://www.emedicinehealth.com/drug-metformin_and_sitagliptin/article_em.htm
Everyday Health, online, 2019, Janumet, [Accessed on the 15th of August 2019], Available at: https://www.everydayhealth.com/drugs/janumet
Omudhome Ogbru, Pharma D, Jay W. Marks, MD Online, What is metformin and sitagliptin, [Accessed on the 15th of August 2019], Available at: https://www.medicinenet.com/metformin_and_sitagliptin/article.htm
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