Candida

Candida infections can be triggered by a variety of general and localized factors. 

General causes include: 

• Antibiotic use: These medications kill bacteria but not the Candida yeast. 
• Hormonal fluctuations: The contraceptive pill and pregnancy can disrupt hormone balance, promoting Candida growth. 
• Chemotherapy: This can weaken the immune system. 
• Chronic illnesses: Conditions like cancer, HIV, and post-transplant recovery can lower resistance. 
• Nutritional deficiencies: Low levels of vitamin B or iron. 
• Diabetes: A reduced immune response may contribute to infections. 

Localized causes vary based on the affected area. 

Candida can infect different parts of the body: 

• Mouth (Oral Thrush): Causes include inhaled medication, poorly fitting dentures, smoking, and dry mouth. 
• Esophagus: Linked to inhaled corticosteroids, intubation, and smoking. 
• Vagina: Hormonal changes and improper pH balance due to soap use are common triggers. 
• Penis: Often occurs due to a tight foreskin or transmission from a partner. 
• Skin and Skin Folds: Moist environments, such as skin folds, increase susceptibility, especially in overweight individuals. 
• Nipples: Breastfeeding can create a warm, moist environment that promotes infection. 
• Nails and Nail Edges: Public spaces like swimming pools pose a risk, especially when the cuticle is damaged. 
• Corners of the Mouth: Poorly fitting dentures can contribute to this form. 
• Generalized Candida: A rare form that occurs when the yeast enters the bloodstream, usually in those with severely weakened immune systems. 

Symptoms vary depending on the infection site: 

• Mouth (Thrush): White patches, sores, and pain when swallowing. 
• Esophagus: Difficulty swallowing, pain near the sternum, and white deposits in the mouth. 
• Vagina: Itching, white discharge, redness, and burning. 
• Penis: Itching, redness, and pain during urination or intercourse. 
• Skin: Red patches, itching, and blisters. 
• Nails: Thick, yellow, crumbly nails, or swollen skin around the nails. 
• Nipples: Redness, pain, and white dots during breastfeeding. 
• Generalized Candida: Severe illness and fever. 

Good hygiene practices are key in managing Candida. Avoid using soap on affected areas and keep them dry. Proper oral care is important for mouth and esophageal infections. Avoid hot foods, acidic products, and alcohol. A healthy lifestyle, including a balanced diet and regular exercise, can help boost resistance to infections. 

Candida infections may resolve on their own, but persistent cases often require medical treatment. Treatment options depend on the infection site and may include antifungal medications such as gels, creams, powders, tablets, or pessaries. In some cases, antibiotics or a combination of medications may be necessary. 

Common antifungal treatments include: 

• Miconazole 
• Clotrimazole 
• Fluconazole 
• Itraconazole 

For vaginal infections, antifungal creams or pessaries are used, while oral medications are preferred for nail infections. Severe or recurring cases may require long-term antifungal therapy. 

In mild cases, Candida may improve on its own. For infants with thrush, cleaning the mouth with a cloth soaked in orange juice can help. Maintain good hygiene, wear breathable clothing, and avoid keeping hands or feet in water for too long. 

Candida is not considered contagious, but vaginal infections can be transmitted to partners. Good hygiene, a balanced diet, and healthy lifestyle habits can help prevent infections. If you suspect an infection, consult a healthcare professional for appropriate treatment. 

Apotheek.nl. (updated on 20 09 2016). Amfotericine B. Referred to on 10 05 2019 on https://www.apotheek.nl/medicijnen/amfotericine-b#belangrijk-om-te-weten-over-amfotericine-b (Viewed on 10 05 2019).

Apotheek.nl. (updated on 15 01 2015). Medications for fungal infections of the skin. Available at: https://www.apotheek.nl/klachten-ziektes/schimmelinfecties-van-de-huid#welke-medicijnen-worden-gebruikt-bij– schimmelinfecties-van-de-huid (Viewed on 10 05 2019).

Farmacotherapeutischkompas.nl. (z.d.). Antimycotic antibiotics. Available at: https://www.farmacotherapeutischkompas.nl/bladeren/groepsteksten/antimycotische_antibiotica (Accessed on 10 05 2019).

Huidinfo.nl . (z.d.) candida of the mouth. Available at:https://www.huidinfo.nl/c/candida-mond/ (Viewed on 10 05 2019).

Isala. (23 November 2018). Patient brochure 5982 Thrush and candidiasis in breastfeeding. Available at: https://www.isala.nl/patientenfolders/5982-spruw-en-candidiasis-bij-borstvoeding/#link2 (Accessed on 10 05 2019).

Medicinfo encyclopedia (z.d.). Perlèche. Available at: https://encyclopedie.medicinfo.nl/ontsteking-van-de-mondhoeken- perleche (Viewed on 10 05 2019).

Mekkes, J.R. (31-12-2016). Fungal nail Lime nail. Available at: https://www.huidziekten.nl/folders/nederlands/schimmelnagel-kalknagel.htm (Viewed on 10 05 2019).

Mekkes, J.R. (05-06-2016). Pronchya. Available at: https://www.huidziekten.nl/zakboek/dermatosen/ptxt/Paronychia.htm (Viewed on 10 05 2019).

MLD foundation (z.d.). What is candida albicans? Available at: https://www.mlds.nl/ziekten/candida-albicans-infectie-met/ (Viewed on 10 05 2019).

Sense. (z.d.). Vaginal candida. Available at: https://www.sense.info/nl/soas/soorten-soas/candida-infectie (Viewed on 10 05 2019).

Schimmelinfecties.com. (z.d.). Fungal infection of the penis. Available at:https://www.schimmelinfecties.com/soorten– schimmelinfecties/schimmelinfectie-aan-de-penis-candida-balanitis/?cn-reloaded=1 (Viewed on 10 05 2019).

Thuisarts.nl. (revised on 2 May 2016) Vaginal Fungal Infection. Available at:https://www.thuisarts.nl/vaginale-afscheiding/ik– heb-vaginale-schimmelinfectie (Viewed on 10 05 2019).