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Pills or Lotion for Hair Loss: Which is More Effective for Men?

Written by: Editors

Modified on: 

Hair loss is a sensitive issue for many men. It can impact self-esteem and daily life. Fortunately, there are treatment options available, such as oral medication and topical lotions. But which is more effective? And can they be used together? This article explores the scientific evidence behind pills and lotions for hair loss.

How Do These Treatments Work?

The two most commonly used treatments for hereditary hair loss (androgenetic alopecia) are finasteride and minoxidil. They function in different ways: 

Product 

Form of Administration 

Mechanism 

Finasteride 

Oral pill 

Inhibits the enzyme 5-alpha-reductase, reducing the production of DHT. DHT is the hormone responsible for shrinking hair follicles. 

Minoxidil 

Topical lotion or foam 

The exact mechanism of minoxidil is not fully understood. It is believed to improve scalp blood flow and prolong the hair growth phase. 

Effectiveness: What Do Studies Show?

Numerous studies indicate that both treatments are effective, though their success depends on the individual and the method of use. 

Treatment 

Results After 6-12 Months 

Remarks 

Finasteride 1 mg/day (oral) 

Stabilisation and increased hair volume in >80% of men 

Possible side effects such as reduced libido in 1-2% 

Minoxidil 5% (topical) 

Hair growth stimulation in 50-60% of men 

Occasional irritation or flaking of the scalp 

Combination (finasteride + minoxidil) 

Higher effectiveness than individually 

Most studied with oral finasteride + topical minoxidil 

Topical finasteride 0.25% + minoxidil 5% 

*Significant hair growth without systemic side effects 

According to a recent pilot study (PMC10495069) 

Oral combination finasteride + minoxidil 

92% experienced stable or improved results (12 months) 

Effective even for severe hair loss (PMC11829753) 

*Further research is required to confirm these findings. 

What Are the Side Effects?

Both treatments can lead to side effects, although these are generally mild. 

Product 

Possible Side Effects 

Finasteride (oral) 

Loss of libido, erectile dysfunction, mood changes (rare) 

Minoxidil (topical) 

Itching, flaking, scalp irritation 

Topical finasteride 

Appears to have a lower risk of systemic side effects 

When Is Combination Useful?

Research suggests that the combination of finasteride and minoxidil is more effective than using either treatment alone. Options include: 

  • Oral finasteride + minoxidil lotion
  • Topical combination solution (such as 0.25% finasteride + 5% minoxidil) 

The choice depends on your preferences, skin sensitivity, side effects, and convenience.   

What Do Doctors Recommend?

According to the NHG Alopecia Guideline, finasteride and minoxidil are proven treatments for hereditary hair loss. Their effectiveness relies on consistent and long-term use (at least 6 months to 1 year). 

Note: Not everyone is suitable for these treatments. Always consult a doctor or one of our affiliated healthcare providers, particularly if you have a history of heart conditions or side effects.   

Conclusion: Choose What Works for You

Both pills and lotions can effectively combat hair loss in men. Combining treatments often yields the best results, especially for early or moderate hair loss. Stay informed, do your research, and consult a doctor to determine the most suitable option for your needs.  

With Doctoronline, we can help you find the right solution tailored to your situation.